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I tend to disagree with using just mesquite for brisket. When I first started smoking a brisket I would use mesquite only and the brisket looked great but in my opinion the smoke flavor was too strong. This may sound disgusting but when you burp the next day and it still tastes like mesquite you might need to try a less potetnt wood. I knwo uses a pecan with a few sticks of mesquite. Just my personal prefernce. Good thread Guy. Anyone else have an opinion?

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smoking with mesquite,not direct grilling,allows the oils from the mesquite to absorb in the meat..Alot of people will get major heartburn for days if too much mesquite is used..thats why most places use a mix of oak and mesquite..I love using a mix of hickory and pecan for most of my smoking..Cherrywood is excellent,but muy expensive..